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Novel Lysosomal Targeting Two-Photon Fluorescence Probe Based on Fluorene Difluoroboron β-diketonate

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We report the synthesis and photophysical characteristics of a two photon fluorescent (2PF) fluorene-based pyridyl difluoroboron-β-diketonate, which when incubated in HCT 116 cells shows superior accumulation in lysosomes in both isolate and encapsulated pluronics.

© 2013 Optical Society of America

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