Abstract

Acoustic-resonance spectrometry (ARS) provides a means of identifying and quantifying materials. A new ARS instrument incorporates a three-transducer design that increases sensitivity through interferometry and uses polyvinylidene fluoride piezoelectric films instead of ceramic transducers to give high output voltages, broader bandwidth, and lower cost. The operating parameters of the ARS are optimized with a widely applicable technique named Universal Numerical Optimization (UNO). The UNO technique allows refinement of instrumental parameters on the basis of distances in hyperspace between sample sets. The new ARS is able to identify different intact tablets and predict the percent dissolution of intact carbamazepine tablets at one hour in a standard apparatus to within 4.6% at a fraction of the cost of traditional or even near-IR methods.

Spectrographic Analysis of Briquetted Tablets*

Harry W. Dietert
J. Opt. Soc. Am. 31(11) 693-696 (1941)

Detection of micro-toxic elements in commercial coffee brands using optimized dual-pulsed laser-induced spectral analysis spectrometry

Ahmed Asaad I. Khalil and Osama A. Labib
Appl. Opt. 57(23) 6729-6741 (2018)

Optical system for tablet variety discrimination using visible/near-infrared spectroscopy

Yongni Shao, Yong He, and Xingyue Hu
Appl. Opt. 46(34) 8379-8384 (2007)

Off-beam QEPAS sensor using an 11-μm DFB-QCL with an optimized acoustic resonator

Roman Rousseau, Zeineb Loghmari, Michael Bahriz, Kaim Chamassi, Roland Teissier, Alexei N. Baranov, and Aurore Vicet
Opt. Express 27(5) 7435-7446 (2019)

Acoustic-resolution photoacoustic microscopy based on an optically transparent focused transducer with a high numerical aperture

Cheng Fang and Jun Zou
Opt. Lett. 46(13) 3280-3283 (2021)