Melanin accumulation in choroid observed with calibrated degree of polarization in PS-OCT

Mengyuan Ke; Mengyuan Ke; Xinyu Liu; Susan Jiang; Jacqueline Chua; Amutha Barathi; Amutha Barathi; Leopold Schemetterer; Leopold Schemetterer

doi:10.1364/OCT.2022.CS4E.2

Biophotonics Congress: Biomedical Optics 2022 (Translational, Microscopy, OCT, OTS, BRAIN)
Technical Digest Series (Optica Publishing Group, 2022),
paper CS4E.2
•https://doi.org/10.1364/OCT.2022.CS4E.2

Melanin accumulation in choroid observed with calibrated degree of polarization in PS-OCT

Mengyuan Ke, Xinyu Liu, Susan Jiang, Jacqueline Chua, Amutha Barathi, and Leopold Schemetterer

Optical Coherence Tomography 2022

Fort Lauderdale, Florida United States
24–27 April 2022
ISBN: 978-1-957171-03-6

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Polarization Sensitive Optical Coherence Tomography (CS4E)

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M. Ke, X. Liu, S. Jiang, J. Chua, A. Barathi, and L. Schemetterer, "Melanin accumulation in choroid observed with calibrated degree of polarization in PS-OCT," in Biophotonics Congress: Biomedical Optics 2022 (Translational, Microscopy, OCT, OTS, BRAIN), Technical Digest Series (Optica Publishing Group, 2022), paper CS4E.2.

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Abstract

Degree of polarization (DOP) measured from polarization sensitive optical coherence tomography (PS-OCT) can reflect the melanin concentration. Here we developed an empirical calibration method to decouple the DOP and intensity and tested on guinea pigs.

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